Areas of expertise

nerve, peripheral, muscle denervation, neurotrophins, sensory crossover, atrophy

Profile

James Bain is a Professor in the Division of Plastic Surgery at McMaster University. Specific research interests include: outcomes following nerve transfers, sensory protection denervated muscle, nerve tension repair, caspase 3 knockout mice denervation, and obstetrical brachial plexus injury (OBPI) outcomes.

Relevant Publications (from the last 5 years)

El Demellawy D, Bain J, Algawad H, Provias JP. Inflammatory pseudotumor of the peroneal nerve: case report and literature review. Ann Diagn Pathol. 2008 Feb;12(1):44-7.

Michalski B, Bain JR, Fahnestock M. Long-term changes in neurotrophic factor expression in distal nerve stump following denervation and reinnervation with motor or sensory nerve. J Neurochem. 2008 Feb 21.

El Demellawy D, Bain J, Provias JP.Inflammatory pseudotumor of the peroneal nerve. Muscle Nerve. 2007 Aug;36(2):271-2.

Batt J, Bain J, Goncalves J, Michalski B, Plant P, Fahnestock M, Woodgett J. Differential gene expression profiling of short and long term denervated muscle. FASEB J. 2006 Jan;20(1):115-7. Epub 2005 Nov 15.

DeMatteo C, Bain JR, Galea V, Gjertsen D. Botulinum toxin as an adjunct to motor learning therapy and surgery for obstetrical brachial plexus injury. Dev Med Child Neurol. 2006 Apr;48(4):245-52. Erratum in: Dev Med Child Neurol. 2006 Sep;48(9):783

Veltri K, Kwiecien JM, Minet W, Fahnestock M, Bain JR. Contribution of the distal nerve sheath to nerve and muscle preservation following denervation and sensory protection. J Reconstr Microsurg. 2005;21(1):57-70.

Zhao C, Veltri K, Li S, Bain JR, Fahnestock M. NGF, BDN F, NT-3, and GDNF mRNA expression in rat skeletal muscle following denervation and sensory protection. J Neurotrauma. 2004 Oct;21(10):1468-78

Labs/Research Institutes

Fahnestock Molecular Biology Lab, McMaster University
Batt Molecular Lab, University of Toronto
Microsurgery Lab, St. Joseph 's Healthcare Hamilton